p-Nitrophenyl carbonate promoted ring-opening reactions of DBU and DBN affording lactam carbamates
نویسندگان
چکیده
The amidine bases DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) and DBN (1,5-diazabicyclo[4.3.0]non-5-ene) display nucleophilic behaviour towards highly electrophilic p-nitrophenyl carbonate derivatives with ring opening of the bicyclic ring to form corresponding substituted ε-caprolactam and γ-lactam derived carbamates. This simple method presents a unified strategy to synthesize structurally diverse ε-caprolactam and γ-lactam compounds with a large substrate scope.
منابع مشابه
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عنوان ژورنال:
دوره 12 شماره
صفحات -
تاریخ انتشار 2016